Upper bound analysis of differential velocity sideways extrusion process for curved profiles using a fan-shaped flow line model

An analytical model for predicting the shapes of rectangular bars with variable curvatures along their lengths through a novel forming method, differential velocity sideways extrusion (DVSE), previously proposed by the authors, has been developed on the basis of the upper bound method. A new flow line function was presented to describe its deformation field. The plastic deformation zone (PDZ) was assumed to be fan-shaped, where the trajectory of the material flow within the PDZ had an elliptic shape. The proposed continuous flow line function was validated using finite element simulations. The flow patterns, extrusion pressure, curvature, and effective strain predicted by the analytical solutions agreed well with modelling results. Compared to the classical discontinuous simple shear model of channel angular extrusion (CAE) with a 90° die, the new approach was shown to predict the effective strain more closely

Sympathetic Blocks Provided Sustained Pain Relief in a Patient with Refractory Painful Diabetic Neuropathy

The sympathetic nervous system has been implicated in pain associated with painful diabetic neuropathy. However, therapeutic intervention targeted at the sympathetic nervous system has not been established. We thus tested the hypothesis that sympathetic nerve blocks significantly reduce pain in a patient with painful diabetic neuropathy who has failed multiple pharmacological treatments. The diagnosis of small fiber sensory neuropathy was based on clinical presentations and confirmed by skin biopsies. A series of 9 lumbar sympathetic blocks over a 26-month period provided sustained pain relief in his legs. Additional thoracic paravertebral blocks further provided control of the pain in the trunk which can occasionally be seen in severe diabetic neuropathy cases, consequent to extensive involvement of the intercostal nerves. These blocks provided sustained and significant pain relief and improvement of quality of life over a period of more than two years. We thus provided the first clinical evidence supporting the notion that sympathetic nervous system plays a critical role in painful diabetic neuropathy and sympathetic blocks can be an effective management modality of painful diabetic neuropathy. We concluded that the sympathetic nervous system is a valuable therapeutic target of pharmacological and interventional modalities of treatments in painful diabetic neuropathy patients

Factors influencing Healthy Eating Habits among Low-Income African Americans in Tennessee

Introduction: Poor nutrition and diet are significant contributors to the development of chronic illnesses such as cancer and diabetes, particularly among individuals of lower socioeconomic status (SES).This study examined demographic and lifestyle factors that influenced decisions to engage in healthy eating behaviors among low-income African Americans in three urban Tennessee cities. Methods: As part of the Meharry Community Networks Program (CNP) needs assessment, a 123-item community survey was administered to assess demographic characteristics and eating behaviors among low-income African Americans. The total sample size was 1116. The primary outcome of interest was the healthy eating habits score which was calculated from a 13-item questionnaire that was part of the community survey. Results: Several statistically significant differences were observed between the mean healthy eating habits scores by sociodemographic variables such as marital status, age, education, and geographic location (P \u3c 0.05). Additionally, significant differences were observed by strategies used for maintaining weight including reducing fat and carbohydrate intake and exercising (P \u3c 0.05). There were also significant differences observed by obstacles to eating low fat foods including family habits and food preparation time (P \u3c 0.05). Discussion: Educational interventions aimed at weight-loss and improving healthy eating should incorporate information about obstacles and predictors to healthy eating